老師個人網站

 個人資料
 姓名 楊鉅文 (Yang Chu-Wen)
 現職 東吳大學微生物學系教授
 專長 基因體學、病毒學、生物資訊學
 電話 02-28819471#6861
 傳真 02-28831193
 電子郵件 ycw6861@scu.edu.tw
 地點 超庸館M201
 導師時間 星期二10:00-12:00 ; 星期四10:00-12:00
 學歷
2000 ~ 2005國立陽明大學 生物化學研究所 博士
 經歷
2006 ~ 2012東吳大學 微生物學系 助理教授
2012 ~ 2016東吳大學 微生物學系 副教授
2016 ~ now東吳大學 微生物學系 教授
 研究主題

Web Site: Biostatistics and Data Visualization using R  https://statistics-using-r.blogspot.tw/

Web Site: Biostatistics and Data Visualization using R  http://blog.xuite.net/stat200635/Biostatistics

Part I. Metagenomics: 這一部分主要是利用大量定序或次世代定序的方法,分析環境中抗抗生素的微生物[13]或分解xenobiotics相關的微生物[1-9,11-12]。以及與中研院及中興大學合作分析中草藥改善雞的腸胃道菌相進而增加抗球蟲感染的能力[10]。

1. Chang BV, Fan SN, Tsai YC, Chung YL, Tu PX, Yang CW*. Removal of emerging contaminants using spent mushroom compost. Sci Total Environ. 2018 Apr 11;634:922-933. doi: 10.1016/j.scitotenv.2018.03.366. ( IF = 4.9; R/C = 22/229 [Q1], ENVIRONMENTAL SCIENCES ) (通信作者)

2. Yang CW, Tsai LL, Chang BV. Fungi extracellular enzyme-containing microcapsules enhance degradation of sulfonamide antibiotics in mangrove sediments. Environ Sci Pollut Res Int. 2018 Apr;25(10):10069-10079. doi: 10.1007/s11356-018-1332-8. (IF = 2.74; R/C = 79/229 [Q2], ENVIRONMENTAL SCIENCES ). (第一作者)

3. Fan CH, Yang CW*, Chang BV*. Anaerobic degradation of sulfamethoxazole by mixed cultures from swine and sewage sludge. Environ Technol. 2017 Oct 10:1-9. doi: 10.1080/09593330.2017.1384510. ( IF = 1.75; R/C = 122/229 [Q3], ENVIRONMENTAL SCIENCES ) (共同通信作者)

4. Yang CW, Chen WZ, Chang BV. 2017. Biodegradation of tetrabromobisphenol-A in sludge with spent mushroom compost. Int. Biodeter. Biodeg. 119:387-395. ( IF = 2.962; R/C = 52/160 [Q2], BIOTECHNOLOGY & APPLIED MICROBIOLOGY ) (第一作者)

5. Yang CW, Huang HW, Chang BV. 2017. Microbial communities associated with anaerobic degradation of polybrominated diphenyl ethers in river sediment. J Microbiol Immunol Infect. 50(1):32-39. ( IF = 2.97; R/C = 50/125 [Q2], MICROBIOLOGY ) (第一作者)

6. Yang CW, Lee CC, Ku H, Chang BV. 2017. Bacterial communities associated with anaerobic debromination of decabromodiphenyl ether from mangrove sediment. Environ Sci Pollut Res. 24(6):5391-5403. (IF = 2.74; R/C = 79/229 [Q2], ENVIRONMENTAL SCIENCES ). (第一作者)

7. Yang CW, Hsiao WC, Fan CH, Chang BV. 2016. Bacterial communities associated with sulfonamide antibiotics degradation in sludge-amended soil. Environ Sci Pollut Res. 23:19754-19763. ( IF = 2.74; R/C = 79/229 [Q2], ENVIRONMENTAL SCIENCES ) (第一作者)

8. Yang CW, Hsiao WC, Chang BV. 2016. Biodegradation of sulfonamide antibiotics in sludge. Chemosphere. 150:559-565. ( IF = 4.208; R/C = 32/229 [Q1], ENVIRONMENTAL SCIENCES ) (第一作者)

9. Yang CW, Chen WZ, Chang BV. 2016. Biodegradation of tetrabromobisphenol-A in sludge-amended soil. Ecol Eng. 91:143-147. ( IF = 2.91; R/C = 74/229 [Q2], ENVIRONMENTAL SCIENCES ) (第一作者)

10. Chang CLT, Chung CY, Kuo CH, Kuo TF, Yang CW*, Yang WC*. 2016. Beneficial effect of Bidens pilosa on body weight gain, food conversion ratio, gut bacteria and coccidiosis in chickens. PLoS One. 11:e0146141. ( IF = 2.806; R/C = 15/64 [Q1], MULTIDISCIPLINARY SCIENCES ) (共同通信作者)

11. Yang CW, Huang HW, Chao WL, Chang BV. 2015. Bacterial communities associated with aerobic degradation of polybrominated diphenyl ethers from river sediments. Environ Sci Pollut Res. 22:3810-3819. ( IF = 2.74; R/C = 79/229 [Q2], ENVIRONMENTAL SCIENCES ) (第一作者)

12. Yang CW, Tang SL, Chen LY, Chang BV. 2014. Removal of nonylphenol by earthworms and bacterial community change. Int. Biodeter. Biodeg. 96:9-17. (IF = 2.962; R/C = 52/160 [Q2], BIOTECHNOLOGY & APPLIED MICROBIOLOGY ) (第一作者)

13. Yang CW*, Chang YT, Chao WL, Shiung II, Lin HS, Chen H, Ho SH, Lu MJ, Lee PH, Fan SN. 2014. An investigation of total bacterial communities, culturable antibiotic-resistant bacterial communities and integrons in the river water environments of Taipei city. J Hazard Mater. 277:159-168. ( IF = 6.065; R/C = 13/229 [Q1], ENVIRONMENTAL SCIENCES ) (第一作者及通信作者)

Part II. Influenza A virus genomics and proteomics: 這一部分主要是自己寫程式來對A型流感病毒的基因體[3]及蛋白質體[1,2]進行分析。

1. Yang CW*, Chen MF. 2016. Uncovering the Potential Pan Proteomes Encoded by Genomic Strand RNAs of Influenza A Viruses. PLoS One. 11(1): e0146936. ( IF = 2.806; R/C = 15/64 [Q1], MULTIDISCIPLINARY SCIENCES ) (第一作者及通信作者)

2. Yang CW*. 2012. A comparative study of short linear motif compositions of the influenza A virus ribonucleoproteins. PLoS One.7(6):e38637. ( IF = 2.806; R/C = 15/64 [Q1], MULTIDISCIPLINARY SCIENCES ) (第一作者及通信作者)

3. Yang CW, Chen SM. 2012. A comparative study of human TLR 7/8 stimulatory trimer compositions in influenza A viral genomes. PLoS One.7(2):e30751. ( IF = 2.806; R/C = 15/64 [Q1], MULTIDISCIPLINARY SCIENCES ) (第一作者)

Part III. Cancer research: 這一部分主要是癌症相關研究,包含我的實驗室發現薑黃素抗肝癌的淋巴癌的能力[1, 6]及我和東吳同事新發現的抗癌胜肽[4]。與陽明大學邱仁輝老師[2,3,5]及蔡亭芬老師[7]合作,協助癌症研究。

1. Liou AT, Chen MF, Yang CW*. 2017. Curcumin Induces p53-Null Hepatoma Cell Line Hep3B Apoptosis through the AKT-PTEN-FOXO4 Pathway. Evid Based Complement Alternat Med. 2017:4063865. ( IF = 1.74; R/C = 10/26 [Q2], INTEGRATIVE & COMPLEMENTARY MEDICINE ) (通信作者)

2. Tseng LM, Chiu JH, Liu CY, Tsai YF, Wang YL, Yang CW, Shyr YM. 2017. A comparison of the molecular subtypes of triple-negative breast cancer among non-Asian and Taiwanese women. Breast Cancer Res Treat. 163(2):241-254. ( IF: 3.626 Rank: 82/217 [Q2], ONCOLOGY )

3. Tsai CH, Chiu JH, Yang CW, Wang JY, Tsai YF, Tseng LM, Chen WS, Shyr YM. 2015. Molecular characteristics of recurrent triple-negative breast cancer. Mol Med Rep. 12:7326-7334. (IF = 1.69; R/C = 85/128 [Q3], MEDICINE, RESEARCH & EXPERIMENTAL )

4. Sung HH, Jane WN, Kao WY, Fu PY, Ho SC, Yang CW*. 2015. Lipopolysaccharide-Binding Motif Derived Peptides Induce Cell Membrane Damages in Human Lung Cancer and Hepatoma Cell Lines. Int J Pept Res Ther. 21:313-324. ( IF = 0.9; R/C = 266/290 [Q4], BIOCHEMISTRY & MOLECULAR BIOLOGY ) (通信作者)

5. Tsai CH, Yang CW, Wang JY, Tsai YF, Tseng LM, King KL, Chen WS, Chiu JH, Shyr YM. 2013. Timosaponin AIII Suppresses Hepatocyte Growth Factor-Induced Invasive Activity through Sustained ERK Activation in Breast Cancer MDA-MB-231 Cells. Evid Based Complement Alternat Med. 2013:421051. ( IF = 1.74; R/C = 10/26 [Q2], INTEGRATIVE & COMPLEMENTARY MEDICINE )

6. Yang CW*, Chang CL, Lee HC, Chi CW, Pan JP, Yang WC. 2012. Curcumin induces the apoptosis of human monocytic leukemia THP-1 cells via the activation of JNK/ERK pathways. BMC Complement Altern Med. 12:22. ( IF = 20288; R/C = 6/26 [Q1], INTEGRATIVE & COMPLEMENTARY MEDICINE ) (第一作者及通信作者)

7. Lin HC, Chen YF, Hsu WH, Yang CW, Kao CH, Tsai TF. 2012. Resveratrol helps recovery from fatty liver and protects against hepatocellular carcinoma induced by hepatitis B virus X protein in a mouse model. Cancer Prev Res (Phila). 5:952-962. (IF = 3.985; R/C = 67/217 [Q2], ONCOLOGY )

Part IV. Miscellaneous: 協助同事數據分析。

1. Chang YT, Yang CW, Chang YJ, Chang TC, Wei DJ. 2014. The treatment of PPCP-containing sewage in an anoxic/aerobic reactor coupled with a novel design of solid plain graphite-plates microbial fuel cell. Biomed Res Int. 2014:765652. ( IF = 2.476; R/C = 67/160 [Q2], BIOTECHNOLOGY & APPLIED MICROBIOLOGY )


 研究成果
 附件檔案